Specification | |
US Brand Name | Antabuse |
Strength | 250mg |
Generic Name | Disulfiram |
Manufacturer | No |
Pharmaceutical Form | Tablet/s |
Dizone-250
Mg
It has a generic name Disulfiram, which is used to treat chronic
and deep rooted alcoholism problem. Disulfiram starts its functioning by
interfering with alcohol metabolism in the body which leads to undesirable and
unpleasant effects when addicted person is consumed alcohol. It is sold under
various trade names including Antabuse and Dizone worldwide. This medicine may
also be given for other treatments which are not listed here.
Important information
about Disulfiram
Notify your doctor, if
you have following conditions before taking Disulfiram: liver or kidney
disease, thyroid problems, diabetes, brain or mental disorders, epilepsy or
other seizure problems. You may not be able to intake Disulfiram altogether
perhaps you may need dose adjustments and close monitoring in case of above
mentioned conditions.
It belongs to the class of FDA pregnancy category C drug. It may
be harmful to your unborn baby while taking during the pregnancy stage. This
medication can pass into the breast milk and can cause harmful effects. You
must consult your doctor before using the tablets in case of pregnancy and
breast feeding.
Before taking Disulfiram
Before taking Disulfiram,
take care of all the above mentioned precautions. Discuss all the conditions
with your doctor and clear all the benefits and side effects pertaining to this
drug.
Dosage information
You should take the
dosage of Disulfiram medication (Antabuse, Dizone), exactly as prescribed by
your doctor. Follow all the direction listed on the leaflet of your medicine.
Take the medicine with the full glass of water. Store all the medicine in a
cool and dry place, far away from the reach of children.
Note: Disulfiram dosage may depend on certain factors including age,
sex, drug allergies, or seriousness of the condition among several other
factors. Your dosage may determined by your physician after examining you
properly.
What if I miss a dose?
For effective results,
you should take all medicines on the same time as prescribed. Missing even a
single dose of Disulfiram can be harmful to your health. However, if you miss a
dose of Disulfiram, then take it instantly, but avoid the use when next scheduled
dose is near.
What if I overdose?
In case of an overdose of
Disulfiram, seek emergency medication because it can cause severe side effects.
Overdose may results into nausea, vomiting, dizziness, loss of co-ordination,
numbness, tingling, or seizures.
Things and activities to
avoid
Avoid drinking alcoholic
beverages while taking Disulfiram, because it can results in nausea, fast
heartbeats, flushing, thirst, chest pain, vertigo, or low blood pressure. You
should not take this medicine for at least 12 hours after consuming alcohol.
Even after you have stopped the use of Disulfiram for several weeks, you may
still see its impact if you drink alcohol. While being treated with this
medicine, you should be very careful and aware of some common medications and
products that contain alcohol in small amounts like cough syrups, mouth wash,
tonics, sauces, vinegars, and several other food products. Go through the
product labels carefully, as alcohol contents in these products may interact
with Disulfiram and yields harmful effects. Some alcoholic fumes from the
products like paints, thinner, solvents may also cause reactions. Be aware of
all these products.
Side Effects
Sometimes, severe liver
problems have been encountered which may convert into death in people taking
Disulfiram even without a prior problem of liver in them. You should consult a
doctor as quickly as possible if you experience some allergic reactions to
Disulfiram (Antabuse, Dizone) such as skin hives, breathing difficulty, swelling
in face, lips, tongue, or throat. Some serious side effects of Disulfiram are
severe lethargy, dark urine, seizures, yellowing of the skin or eyes, drastic
changes in appetite, severe diarrhea or vomiting. While, some common or less
serious side effects are skin rash, acne, mild headache, mild drowsiness or
tiredness, impotence, unpleasant metallic taste, swollen or sore tongue. These
are not all the side effects mentioned above. There may be others as well.
Interaction with other
drugs
Inform your doctor well
in advance, if you are taking any kind of medications (prescription, OTC,
herbal), before he/she prescribes you Disulfiram medicine. Tell your doctor
about any of these medicines to avoid harmful effects as these drug may
interact with Disulfiram- a monoamine oxidase inhibitor like isocarboxazid,
phenelzine, or others; isoniazid; a benzodiazepine such as diazepam,
chlordiazepoxide, clorazepate, or others; a tricyclic antidepressant such as
amitriptyline, imipramine, doxepin, or others; warfarin; metronidazole;
lithium; phenytoin; or theophylline. Always consult your doctor about
starting a new medication.
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