Sorafenat 200 mg (Nexavar)
US Brand Name Nexavar
Strength 200mg
Generic Name Sorafenib
Manufacturer Natco, India
Pharmaceutical Form Tablet/s

Sorafenat 200mg


Sorafenat is an anti-cancer drug used as a chemotherapeutic medicine. This medicine is used to treat advanced renal cell carcinoma, a type of kidney cancer, radioactive iodine resistant advanced thyroid carcinoma and advanced primary liver cancer.


How it works?


Sorafenat works by interfering with growth and spread of cancer cells in the body. This medicine blocks protein kinases and stops the cancer cells from forming blood vessels required for their growth.


Important information about Medicine


Sorafenib is a Tyrosine Kinase Inhibitor and Angiogenesis Inhibitor. This medicine interferes with the signaling mechanism of enzymes and thus slows down the growth of cancer cells considerably.


Dosage information


Doctor would decide on the dosage and patient needs to take this medicine empty stomach. The medicine needs to be swallowed with water and should not be broken, crushed or chewed.


Strengths available


Sorafenat is available in the strength of 200mg.


What if you miss a dose?


In case, you miss the dose take it as soon as you remember. If the time to next dose is near, skip the missed one and follow the schedule.


What if you overdose?


Do not alter the dose, in case you take multiple doses, get in touch the local poison center immediately. In case you notice symptoms such as diarrhea or severe skin rashes and burns, get in touch with your doctor immediately.


Things to be taken care of


When taking Sorafenat ensure that you follow all the instructions provided by the doctor and do not take any restricted foods or beverages. Intake of this medicine can cause high blood pressure; in case you are a patient of hypertension discuss this with your doctor before taking this anti cancer drug. If you are pregnant, lactating or trying to conceive do not take this medicine unless instructed by the doctor. Tell your doctor if suffering from kidney or liver diseases or if you have blood clotting disorder.


Side Effects


Possible side effects that could bother some and not all after taking in Sorafenat are:

§  Increased Blood Pressure

§  Black, Bloody, Or Tarry Stools

§  Sudden Numbness Or Weakness

§  Headache

§  Constipation

§  Diarrhea

§  Stomach Pain

§  Trouble Breathing

§  Dry Or Itchy Skin

Do not take any of these side effects lightly and seek medical assistance from a health care practitioner on time.


Interaction with other drugs


Constituents present in Sorafenat might interact with several drugs, supplements, foods and beverages. The drugs that could show severe interactions are:

§  Bosentan

§  Montelukast

§  Arsenic Trioxide

§  Selegiline

§  Voriconazole

§  Clarithromycin

§  Rifampin

§  Anti-Malaria Medications Such As Chloroquine

§  HIV Medication

§  Droperidol

§  Medicines To Treat Narcolepsy

§  Seizure Medication Such As Carbamazepine

§  Type 2 Diabetes Medications Such As Glimepiride


This is not a complete list, so, in case you are taking any medicine or have been a drug in past inform your doctor about it before taking this anti cancer drug.


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Sorafenat 200 mg (Nexavar)

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  • Product Code: Sorafenat 200 mg (Nexavar)
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