What is Simvotin

Simvotin most often called as Simvastatin which belongs to a class of drugs HMG CoA reductase inhibitors or ‘statins’.  It lowers down low density lipoprotein (labeled as LDL) and triglycerides in the blood, while increases the level of high density lipoprotein drugs (labeled as HDL). Increase in the LDL can lead to heart stroke, heart attack and other cardiovascular diseases in patients who have diabetes, coronary heart disease, or other risk factors.

Simvastatin is sold under various trade names including Zocor (Fako Pharma), Simlup (made by Lupin), and Simvotin (made by Ranbaxy).

Important information about Simvastatin

You should not take Simvastatin if you are strictly allergic to it. Additionally, if you are pregnant or breast feeding and having liver disease, stop the use of this drug and inform your doctor immediately. Before taking Simvastatin, let your doctor know if you have kidney disease, diabetes, thyroid problems or if you take more than 2 drinks of alcohol daily. It has been acclaimed that myopathy has higher in those patients who belongs to Chinese descent (0.43%) as comparison to those who are not Chinese descent.

In abnormal situations, Simvastatin ingestion results in the breakdown of skeleton muscle tissue and kidney failure. If you have unexplained pain in muscles, tenderness, or weakness especially due to unusual fatigue, fever and dark colored urine. In order to retain the maximum benefits, you must avoid high fat diet. If you are taking alcohol too much, then this drug is no more useful to you as consumption of alcohol increases triglyceride levels which in turn results to liver damage. Simvastatin is a part of full line treatment for cholesterol which includes diet restrictions, a proper regimen, exercises and other medicines. Make sure to follow the instructions given by your doctor and keep your cholesterol level check. It belongs to the FDA pregnancy category X drug. It can cause harm to your unborn baby if taken during the pregnancy stage. Use of effective birth control measure is recommended while you are having the medicinal treatment with Simvastatin.  

Before taking Simvastatin

Before taking simvastatin, you should discuss all the conditions with your doctor and clear all the doubts pertaining to this drug.

Dosage Information

Take Simvastatin as per your doctor’s direction and refer the medicine leaflet to know more details about this drug. Do not alter the dosage without your doctor permission. Also, do not take this medicine after prescription period time is over. This drug usually can be taken at the bed time or with an evening meal. You may need to have this medicine for a long time period to maintain the cholesterol level. But, in case you have some serious disorders like uncontrolled seizures, an electrolyte imbalance, severely low blood pressure, a severe infection or illness, dehydration, or surgery or a medical emergency, you have to temporarily suspend the use of Simvastatin. Always store this medicine in a cool and dry place.

What if you miss a dose

If you miss a dose of Simvastatin, take the drug as soon as possible. Be aware to skip the dose if the next dose time is close. Taking multiple dose of Simvastatin can lead to excessive medicine in your body which might cause critical conditions.

What if you overdose

In case of overdose, get emergency medical help or call your doctor immediately.

Things to avoid

Do not take the antacids without your doctor’s advice and prefer only those which are recommended by your doctor. In some urgent conditions, you must take the antacid medicine after at least 2 hours of taking Simvastatin. Avoid, high fat diet, alcohol and grapefruit based products while being treated with Simvastatin.

Side Effects

Simvastatin causes some mild memory or confusion problems, but in rare case it results in foamy urine. Contact your doctor immediately, if this serious condition persists. It may also cause breakdown of skeletal muscle tissue, causing kidney failure, liver damage, yellowing of eye and skin, dark urine, severe stomach or abdominal pain, or persistent nausea or vomiting. Seek medical attention immediately to get the treatment.

Interaction with other drugs

Some other drugs may interact with Simvastatin and causing muscle pain. Inform your doctor in advance, if you are taking other medicines or products like: amiodarone, colchicines, danazol, ranolazine, medicines that contain niacin, cimetidine, conivaptan, imatinib, isoniazid, drugs that lower immune system (such as anti cancer drugs, steroids, or immunosuppressive drugs used after organ transplant), diltiazem, gemfibrozil, fenofibrate, spironolactone, or other statin drugs such as rosuvastain, atorvastatin, fluvastatin, pravastatin, or lovastatin. 

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