How Malegra 50 works?Malegra 50 having Sildenafil citrate works by inhibiting the phosphodiesterase type 5 in the body. Thus it stops the degradation of cGMP( Cyclic guanosine monophosphate). Availability of cGMP helps relax the veins in penis and thus helps in erection when there is need for sexual activity or sexual stimulation. 

Inhibition of phosphodiesterase type 5 (PDE-5) in smooth muscle of pulmonary blood vessels results in its relaxation of and it help to reduce the pressure in your lungs.

How to take Malegra 50?
Malegra 50 having salt Sildenafil citrate shall be taken before 1 hour of sexual intercourse with a glass of water. More information will be directed by your doctor. Hence consult your doctor before having Malegra 50.

Dosage
Sildenafil citrate the active salt in Malegra 50 is to be taken usually in dosage which ranges from 25 mg to 100 mg. More specific dose will be directed by your doctor. Hence, do not take Malegra 50 without consulting with your doctor.

How long should Malegra 50 be continued?
Malegra 50 having sildenafil citrate is need to basis medicine. Consult your doctor regarding the intake and stoppage of the drug. Do not take decision on your own. Consult your doctor for each possible steps.

Dose of Malegra 50 missed
The possible chances of missing the dose of the drug is minimal, however, consult your doctor regarding the same. The drug is mainly taken before the actual sexual intercourse, hence missing the dose is rare.

Drug interaction with Sildenafil citrate the salt in Malegra 50

• Nitrates(Isosorbide dinitrate, isosorbide mononitrate, nitroglycerin) generally react with Sildenafil citrate, the salt present in Malegra 50.
Tell your doctor
• If you are taking any of these drugs: Itraconazole or ketoconazole, riociguat, or ritonavir, rifampin. 
• If you are taking another brand that has the same active ingredient (sildenafil citrate) 
• If you are taking another drug in the same class as of sildenafil citrate (eg:tadalafil)
• If you are taking any of these drugs-alfuzosin, doxazosin, silodosin, tamsulosin, terazosin

When not to take Malegra 50
Do not take Malegra 50 if you have allergic reactions with the salt or excipients.

Adverse Effects / Side effects of Malegra 50
• Some patients may have allergic reactions. Inform your doctor if you have any signs of allergic reaction like rash, itching, red-swollen skin, fever, trouble breathing, swollen face etc.
• Chest pain or pressure 
• A fast heartbeat or a heartbeat that does not feel normal. 
• Dizziness or passing out. 
• Severe headache. 
• Weakness on one side of the body, trouble speaking or thinking, loss of balance, drooping on one side of the face, or blurred eyesight. 
• Change in eyesight. 
• Loss of eyesight. 
• Hearing loss or change in hearing
• Ringing in ears. 
• Very bad muscle pain, back pain, soreness, or weakness. 
• If you have a painful erection (hard penis) or an erection that lasts for longer than 4 hours, then call your doctor immediately. It should be treated properly otherwise it may cause lasting sex problems.

Overdose Effects of Sildenafil citrate the salt in Malegra 50
Possible effects of overdosage depends upon person to person. However, the effects include painful and prolonged erection. Also it can result in dizziness and discomfort. Consult your doctor immediately if you are having any of this effects.

General information and Precautions
Tell your doctor;
• If you have an allergy to sildenafil citrate or  excipients in the formulation.
• If you are allergic to drugs like sildenafil (eg:tadalafil) or to any other drugs or foods.( Inform your doctor if you have any signs of allergic reaction like rash, itching, red-swollen skin, fever, trouble breathing, swollen face etc.)
• If you have kidney disease or liver disease. 
• If you had heart attack within the last 90 days.
• If you have chest pain during sex, heart failure, an abnormal heartbeat, high or low blood pressure, or a stroke within the last 6 months. 
• Older people (65 or older) may have more side effects. So use this drug with care.
• If you are, use this drug with care. You could have more side effects.