Cosart-H - 50/12.50 mg (Hyzaar)
US Brand Name Hyzaar
Strength 50/12.50 mg
Generic Name Losartan Potassium + Hydrochlorothiazide
Manufacturer Cipla
Pharmaceutical Form Tablet/s

Cosart-H-50/12.50 MG


This drug has a generic name Losartan Potassium and Hydrochlorothiazide which is a combination medicine for hypertension (high blood pressure) that constitutes two active ingredients, Losartan Potassium and Hydrochlorothiazide. The first constituent Losartan Potassium is an angiotensin II receptor antagonist that prevents blockage of blood vessels, thereby, improves blood flow and lowers the blood pressure. It is also used to reduce the risk of heart stroke in certain people who have heart disease. While, the second active ingredient Hydrochlorothiazide is a thiazide dieuretic (water pill) that stops the body from absorbing too much salt that retain which results in fluid retention. Increased level of salt in the body can lead to high blood pressure. It is sold under various trade names including Hyzaar and Losacar H (made by Cipla).



Important information about Losartan Potassium and Hydrochlorothiazide

Strictly avoid the consumption of Losartan Potassium and Hydrochlorothiazide (Hyzaar, Losacar H), if you are allergic to it, or if you are unable to urinate. In order to make sure that this drug is fine for you, inform your doctor in advance if you have any of the following conditions: heart disease or congestive heart failure, kidney disease (or if you are on dialysis), liver disease, lupus, gout, glaucoma diabetes, asthma, or an allergy to sulfa drugs or penicillin.


It belongs to the pregnancy category D drug. You should not take this drug in pregnancy stage because it can cause injury or death of an unborn baby if pregnant women take it in second or third trimester. Use of an effective birth control measure can be helpful during this medicinal treatment. Do not take this medicine without the permission of your doctor if you are breast feeding. In case you become pregnant during this medicine based treatment, inform your doctor immediately and stop taking this tablet. Losartan Potassium may increase your potassium levels; hence avoid the consumption of potassium based supplements during the treatment. In rare cases, this drug can result into the breakdown of skeletal muscle tissue, causing in kidney failure. Immediately find the medical treatment if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual fatigue, and dark colored urine problems.



Before taking Losartan Potassium and Hydrochlorothiazide


You should take care of all the above mentioned precautions mentioned above before taking Losartan Potassium and Hydrochlorothiazide (Hyzaar, Losacar H). Discuss them with your doctor and clear all the doubts about this medicine.



Dosage Information


You should take Losartan Potassium and Hydrochlorothiazide according to your doctor’s permission. Do not alter the dosage unless your doctor advices you to do so. Do not take the medicine if the prescription period is over. Always refer the instruction listed on the medicine leaflet while taking the medicine. This medicine may take up to 4 weeks of regular intake to show the positive effect over high blood pressure. It can be taken with or without food and you should swallow the tablet as a whole with full glass of water. Always store the tablet in a cool and dry place.     

While taking Losartan Potassium and Hydrochlorothiazide, watch out for the symptoms like vomiting, diarrhea or excessive sweating. All these conditions can lead to severe dehydration which can further lower down your blood pressure. It can be very dangerous as it may cause fatal conditions. Consult your doctor if any of these conditions occur. You may have to take this medicine for many years, even you may feel better.



What if you miss a dose


If you miss a dose of Losartan Potassium and Hydrochlorothiazide, try to take as soon as you remember the dose. Always take care that you should not take the missed tablet if the next dose time is close.



What if you overdose


In case of overdose, seek for an emergency medical treatment or call the Doctor. Overdose may cause nausea, weakness, dizziness, dry mouth, thirst, muscle pain, weakness, or a feeling like you might pass out.    



Things and activities to avoid


Avoid or limit the consumption of alcoholic beverages. Do not become overheated or dehydrated during the exercises and hot weather time. Always follow your doctor’s instruction about what type of fluid you should prefer in your diet. It can increase the potassium level in your body; hence avoid the intake of potassium based supplements.       



Side Effects


Dizziness, light headedness, swelling in ankles or feet, or flushing are some common side effects that may be encountered during the usage. Also, some serious side effects are there like fast, irregular or rapid heartbeat, or fainting, etc, which may worsen the situation.  Seek medical attention immediately and contact your doctor right away.



Interaction with other drugs


Many others drug may interact with Losartan Potassium and Hydrochlorothiazide, inform your doctor well in advance if you are using following products: (OTC vitamin pills or other medicines, or herbal products), especially other blood pressure medicines, cholestyramine, cyclosporine, rafmapin, ritonavir, barbiturates, muscle relaxers, narcotic medicines, lithium, NSAIDs (ibuprofen, naproxen, or others), steroids, cholestyramine, colestipol, insulin, oral diabetes medicines, a potassium supplement such as K-Dur, Klor-Con, salt substitutes that contain potassium, or diuretics. However, these are not only the drugs which interact with Losartan Potassium and Hydrochlorothiazide. Never start a new medication without your doctor permission.   


We at For Daily Medicine, provides generic medicine for heart and blood pressure and all other kind of diseases. You can buy Cosart-H-50/12.50 MG online at no risks to get the best cure of your hypertension.

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Cosart-H - 50/12.50 mg (Hyzaar)

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