Ciplin - 400 + 80 mg (Septra DS)
US Brand Name Septra DS
Strength 400 + 80 mg
Generic Name Sulfamethoxazole Trimethoprim
Manufacturer GSK
Pharmaceutical Form Tablet/s

CIPLIN 400 80mg


Ciplin is an antibiotic that is quite effective against various bacterial infections such as Escherichia coli, Stenotrophomonas maltophilia, Staphylococcus epidermidis, Bacteroides fragilis, Pseudomonas aeruginosa, N.Gonorrhea, Haemophilus influenza, Staphylococcus saprophyticus and N.Syphilis.



How it works?


Ciplin restricts and prevents the growth of bacteria by inhibiting folic acid synthesis. This antibiotic binds with PABA and this ends the folic acid production. In this way, the growth of bacteria stops.



Important information about Medicine


Sulphamethoxazole Trimethoprim is a synthetic antimicrobial drug with a broad spectrum bactericidal action. This antibiotic is active against gram positive bacteria. This medicine is used for treating Urinary tract infections, Sexually transmitted diseases, Pharyngitis, Bronchitis, Sinusitis, skin structure infections, Traveler’s diarrhea and acute otitis media.



Dosage information


You need to take the dosage prescribed by the doctor. The doctor would decide on the dosage looking into the type of infection and its spread. Make sure that you complete the dosage course.



Strengths available


Ciplin is available in the strength of 400+ 80mg.



What if you miss a dose?


Make sure that you take each dose on time as this could prevent you from skipping any dose. In case, you miss a dose, take it as soon as you realize. Do not mix two doses, try and maintain the time gap suggested by your doctor.



What if you overdose?


Do not alter the dose recommended by the doctor as an overdose could lead to toxicity. In case you overdose, get in touch with your doctor or visit a nearby medical emergency center right away.



Things to be taken care of


You should not take Ciplin if you are hypersensitive to Sulphamethoxazole Trimethoprim or if suffering from HIV or if you have porphyria. Breast feeding and pregnant women need to consult with the doctor before taking this medicine. If you have thyroid problem, asthma, folic acid deficiency or anemia, notify your doctor about this before you begin taking Ciplin.



Side Effects



Common side effects of Ciplin that might bother some are:

§  Flu

§  Diarrhea

§  Stomach disturbances

§  Jaundice

§  Sores in the mouth

§  Low sodium levels in the body

§  Fever, hives and chills

§  Watery or bloody diarrhea

§  Mild itching

§  Swollen glands

§  Vomiting

§  Stiffness of muscles and joints

§  Rashes on the skin


In case, any of these symptoms occur, get in touch with a local pharmacist or your doctor immediately.



Interaction with other drugs


It is important to know that there are certain drugs that could cause interaction with Ciplin, these are:

§  Warfarin

§  Enalapril

§  Dofetilide

§  Phenytoin

§  Levorucin

§  Rifampin

§  Valproic acid

§  Digoxin

§  Methotrexate


If taking any of these, inform your doctor so that he could work on the other alternatives.

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Ciplin - 400 + 80 mg (Septra DS)

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