Nizral Solution (Shampoo) - 2% (50 ml)

This drug constitutes a generic name Ketoconazole, used for the treatment of certain fungal infections in the body or serious infections on nails and skin. This drug is fall under the category of drugs known as Azole antifungals and functions by stopping the growth of fungus.  

It is available in various forms such as tablets, cream and shampoo and marketed under various brand names viz. Nizoral and Nizral (both made by Johnson & Johnson).

Important information about Ketoconazole

This solution should not be applied if you are allergic to it, or if you are taking triazolam. Before using Ketoconazole, inform your doctor if you have following conditions: liver disease, kidney disease, a heart rhythm disorder, or a history of Long QT syndrome. You must use this medication for the entire prescribed time, even after all the symptoms have vanished. However, the infection may still not be wiped out from your body. Not taking this medicine as prescribed by your doctor can worsen your condition and cause a severe infection which cannot be treated through drugs.

Ketoconazole is a FDA pregnancy category C drug. It may be harmful to your unborn baby while taking during the pregnancy stage. This medication can pass into the breast milk and can cause harmful effects. You must consult your doctor before using the tablets in case of pregnancy and breast feeding.

Before taking Ketoconazole

Before applying Ketoconazole antifungal solution, take care of all the above mentioned precautions. Discuss all them with your doctor and clear your doubts which you may have about this medicine.

Dosage Information

Use Ketoconazole antifungal solution (Nizoral, Nizral) exactly as your doctor prescribed. Do not alter the dosage unless your doctor advices you to do so. Prohibit the use of this drug if the prescription period is over. All medicines come along with a patient leaflet; you should go through the leaflet to know detailed information. Always store the medicine in a cool and dry place.   

Note: Ketoconazole dosage depends on lots of factors like age, sex, drug allergies, or seriousness of the condition, your doctor may fix the dosage by examining you properly. Strictly follow the dosage instruction prescribed by your doctor.    

What if you miss a dose

If you miss a dose of Ketoconazole, take it as soon as you remember. Don’t take the missed one dose if the next dose time is close.   

What if you overdose

In case of an overdose, seek medical attention immediately or contact your doctor.  

Things and activities to avoid

Do not consume antacids or other acid reducer drugs for at least 2 hours after you have taken Ketoconazole as they can effect on the functionality of this medicine and thereby make the absorption of this drug harder. Avoid the consumption of alcohol while taking Ketoconazole as it may cause side effects. While using Ketoconazole topical form, avoid covering the medicated skin areas. Try to avoid tight fitting attire and synthetic cloths. If you are using this medicine for jock itch in your feet, wear clean cotton socks, sandals or shoes which permit proper air flow to the affected area.     

Side Effects

Some common side effects caused by this medicine are nausea and vomiting. If any of these side effects will continue or deteriorate, get medical care immediately. In some rare cases, it may cause the following conditions: adrenal gland problem (adrenal insufficiency), low testosterone levels, or low sperm production when used at high doses.  These are not all the side effects mentioned above. There may be others as well.

Interaction with other drugs

Many other drugs can interact with Ketoconazole including a blood thinner like warfarin or clopidogrel, alfentanil, cyclophosphamide, cyclosporine methadone pimozide prednisone saquinavir, sirolimus, tacrolimus, theophylline, voriconazole, antidepressants, cancer medicines, cholesterol lowering medicines, heart or blood pressure medicines, NSAIDs, oral diabetes medicines, rifabutin, sedative drugs, or seizure medicines. However, these are not the full list of drugs that may interfere with it. There may be some others. Never start a new medication unless your doctor advised you to do so.

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