Specification | |
US Brand Name | Janumet |
Strength | 50+1000mg |
Generic Name | Sitagliptin+ Metformin |
Manufacturer | No |
Pharmaceutical Form | Tablet/s |
Janumet -
50+1000mg
This drug has a generic name Sitagliptin which is an oral
medicine for diabetes problems. It is marketed with the name of salt of
phosphate under various trade names. This drug is very effective in controlling
the sugar level, thereby, controlling diabetes. It is mostly recommended to
treat Type 2 diabetes mellitus alone or in combination with other complimentary
medicines which are used to cure diabetes. This drug is not recommended for
type 1 diabetes. It is either sold alone or in combination with metformin or
Thiazolidinediones (other anti-hyperglycemic agents).
How
it works?
Sitagliptin is an oral
anti-hyperglycemic or anti-diabetic drug which comprised of DPP-4 inhibitors
(dipeptidylpeptidase-4 inhibitors) that helps in lowering down the blood sugar
level. These inhibitors increase the secretion of insulin and suppress the
release of glucagon by pancreas. This derives the glucose levels to the normal
level. As the blood glucose levels become normal, the increased changes in the
insulin and glucagon halts and thus further prevents from hypoglycemic
situation.
Important
information about Sitagliptin
You should avoid this
drug if you are allergic to it or any of its constituents present in it. Avoid
taking this medicine if you are pregnant or planning to become pregnant, have
type-1 diabetes mellitus, have diabetic ketoacidosis, severe kidney problem,
have pancreatitis and serious infections.
Dosage
information
It is very important to
follow your doctor’s instruction while taking this medicine. Never stop taking
this medicine until your doctor advices you to do so. Take the medicine about
the same time each day because it is the best practice to remember when to take
the drug. Do not alter the dosage unless your doctor advises you to do so.
Also, do not take this medicine after the prescription period is over.
Swallow the tablet with one glass full of water. The drugs should preferably be
combined with meals to obtain the optimum benefits. You should follow a well-balanced
calorie controlled diet (rich in fruits and vegetables) while taking this
medicine.
Strengths
available
The drug is available in
the varying strength of the active ingredient Sitagliptin such as Januvia 25 mg
tablet, Januvia 50 mg tablet, Januvia 100 mg tablet
The combination drug of Sitagliptin and metformin is also
available in strength of Janumet 50+500mg and Janumet 50+1000mg.
This medicine controls over diabetes but not cure it. Hence, it
is needed to take this medicine for a longer time as your doctor prescribed.
What
if you miss a dose?
In case you miss a dose
of Sitagliptin, skip the dose and take the next one on time. If it’s too late
but less than 1 hour of the meal, then you can take it normally as you would.
Don’t double up the dose in order to compensate with the missed one.
What
if you overdose?
In case of an overdose of
Sitagliptin, you may suffer from harmful side effect such as hypoglycemia (low
blood sugar). Seek medical emergency in this situation. Contact your doctor or
get medical care if you experience following conditions: Back, muscle
or joint pain, abdominal pain (severe or mild), headache, nausea,
osteoarthritis, constipation, diarrhea, dizziness.
Things
to be taken care of
Do not consume alcohol.
Do not skip the meals while being treated with this medication. Always keep a
source of sugar available with you like a fruit or candy or gel. Keep a regular
checkup on your blood sugar level and body weight. Never change the dose until
your doctor’s permission.
Side
Effects
Inform your doctor as
soon as possible if you witness any of the following side effects- soreness in
the back of the nose, unusual tiredness, low blood sugar, headache and
drowsiness, fast heart rate, feeling drunk, headache, constipation, diarrhea,
dizziness and trouble concentrating, unusual bleeding or bruising. In all these
conditions, seek medical care immediately. Do not get alarmed by the list. You
may/may not experience all of these side effects.
Interaction
with other drugs
As this drug is relevant
to weight loss, ask your doctor about the intake of the cholesterol and
diabetes drugs. Consult your doctor if you are taking these medicines-
Ivacaftor, Probenecid, Non-steroidal anti-inflammatory drugs, Aspirin or other
salicylates, Sulfa drugs, Monoamine oxidase inhibitors, Beta-blockers. Ask your
doctor to get the full details about the medicines which may interact with this
medicine. Also tell him about the herbal or OTC medicine that you may be using.
Never start a new medication until your doctor advices you to do so.
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