Specification | |
US Brand Name | Lexxel |
Strength | 5 + 2.5 mg |
Generic Name | Enalapril + Felodipine |
Manufacturer | Cipla |
Pharmaceutical Form | NA |
Enam
+ Plendil - 5 + 2.5 mg
It has a generic name Enalapril and Felodipine made up by
the combination of two active ingredients Enalapril and Felodipine which is
used to treat hypertension or high blood pressure. It is usually prescribed
after other medications failed to reign in high blood pressure. Enalapril is an
ACE (angiotensin converting enzyme) inhibitor drug. And, the other active
constituent Felodipine is a calcium channel blocker which relaxes the muscles
of the heart and blood vessels. It is sold under various trade names including
Lexxel, Enam+Plendil (made by Cipla) among several other brands around the
world.
Important
information about Enam + Plendil
You should not take
Enalapril and Felodipine (Lexxel, Enam+Plendil), if you are strictly allergic
to it or any other ACE inhibitor drugs like ramipril, captopril, fosinopril,
benazepril, moexipril, and others. Prior taking this medicine, you must inform
your doctor if you have following conditions: congestive heart failure, kidney
disease (or if you are on dialysis), liver disease, low sodium levels in your
body (hyponatremia), diabetes, or a history of blood clot or stroke. If you
have any of these conditions, you must require dose adjustments or special
medication tests before taking this medicine.
This drug belongs to pregnancy category D drug. Hence,
care should be taken if you are pregnant woman. In case you become pregnant
during the drug ingestion, contact your doctor immediately. It can cause
harmful effects and might even results in death of an unborn baby, if a pregnant
woman take it in second or third trimester. Do not take this medicine without
the permission of your doctor if you are breast feeding. Use of an effective
birth control measure should be required during the treatment with this
medicine. If you are being treated for high blood pressure, continue the use of
this medicine even if you don’t encounter any symptoms. High blood pressure
doesn’t have any outwardly signs. Blood pressure medicine may be required to be
taken for a long time period.
Before
taking Enalapril and Felodipine
You should take Enalapril
and Felodipine strictly according to your doctor’s guidance and inform your
doctor in advance about the following conditions: congestive heart
failure, kidney disease (or if you are on dialysis), liver disease, low sodium
levels in your body (hyponatremia), diabetes, or a history of blood clot or
stroke, in order to prevent serious health issues. Before taking Enalapril and
Felodipine (Lexxel, Enam+Plendil), take care of all the above mentioned precautions
and clear all the doubts about this medicine.
Dosage
Information
You should take the
dosage of Enalapril and Felodipine exactly as prescribed by your doctor. Follow
all the direction listed on the leaflet of your medicine. Do not alter the
dosage until it is being advised by the doctor. Also, do not use the medicine
after prescription period is over. Store all the medicine in a cool and dry
place, far away from the reach of children. Enalapril and Felodipine can be
taken with or without having the food.
Note: Enalapril and Felodipine dosage may depend on certain
factors including age, sex, drug allergies, or seriousness of the condition
among several other factors. Your dosage may determined by your physician after
examining you properly.
What
if you miss a dose
You should take your
medicine on the same time as prescribed by your doctor. If you miss a dose of
Enalapril and Felodipine for unforeseen reasons, then take it instantly, but
avoid the use when next scheduled dose time is close.
What
if you overdose
In case of an overdose of
Enalapril and Felodipine, get emergency medication care as it can cause severe
dizziness, light headedness, or fainting.
Things
and activities to avoid
Alcoholic beverages must
be avoided while taking this medicine as alcohol can further reduce blood
pressure. Also, avoid activities which require high metal acquisition and
reflexes (driving). You should prohibit the use of potassium based supplements
and salt substituent that contain potassium while you are being treated with
this medicine.
Side
Effects
Some common side effects
caused by Enalapril and Felodipine are dizziness, light headedness, tiredness,
or headache. If any of these effects persists or deteriorate, contact your
doctor or seek medical attention right away. A serious side effect is unlikely
and cause severe effects to your health. However, if you experience some
serious side effects due to the elevated level of potassium in your body like
(fast, irregular or rapid heartbeat, muscle weakness), fainting, decreased or
no urination, seek the medical attention right away.
Interaction
with other drugs
Many other drugs can
interact with Enalapril and Felodipine, some of them are (OTC vitamin pills or
other medicines, or herbal products), especially cemitidine, lithium, NSAIDs
(ibuprofen, naproxen, or others), HIV/AIDS medicines, certain antibiotics (clartithromycin,
erythromycin, or others), seizure medicines, certain antidepressants, or a
diuretic. Let your doctor know in advance if you are using such medicines
before starting the use of Enalapril and Felodipine.
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