Specification | |
US Brand Name | Hyzaar |
Strength | 50/12.50 mg |
Generic Name | Losartan Potassium + Hydrochlorothiazide |
Manufacturer | Cipla |
Pharmaceutical Form | Tablet/s |
Cosart-H-50/12.50
MG
This drug has a generic
name Losartan Potassium and Hydrochlorothiazide which is a combination medicine
for hypertension (high blood pressure) that constitutes two active ingredients,
Losartan Potassium and Hydrochlorothiazide. The first constituent Losartan Potassium is an angiotensin II receptor
antagonist that prevents blockage of blood vessels, thereby, improves blood
flow and lowers the blood pressure. It is also used to reduce the risk of heart
stroke in certain people who have heart disease. While, the second active
ingredient Hydrochlorothiazide is a thiazide dieuretic (water pill) that stops
the body from absorbing too much salt that retain which results in fluid
retention. Increased level of salt in the body can lead to high blood pressure.
It is sold under various trade names including Hyzaar and Losacar H (made by
Cipla).
Important
information about Losartan Potassium and Hydrochlorothiazide
Strictly avoid the consumption of Losartan Potassium and
Hydrochlorothiazide (Hyzaar, Losacar H), if you are allergic to it, or if you
are unable to urinate. In order to make sure that this drug is fine for you,
inform your doctor in advance if you have any of the following conditions:
heart disease or congestive heart failure, kidney disease (or if you are on
dialysis), liver disease, lupus, gout, glaucoma diabetes, asthma, or an allergy
to sulfa drugs or penicillin.
It belongs to the pregnancy category D drug. You should
not take this drug in pregnancy stage because it can cause injury or death of
an unborn baby if pregnant women take it in second or third trimester. Use of
an effective birth control measure can be helpful during this medicinal
treatment. Do not take this medicine without the permission of your doctor if
you are breast feeding. In case you become pregnant during this medicine based
treatment, inform your doctor immediately and stop taking this tablet. Losartan
Potassium may increase your potassium levels; hence avoid the consumption of
potassium based supplements during the treatment. In rare cases, this drug can
result into the breakdown of skeletal muscle tissue, causing in kidney failure.
Immediately find the medical treatment if you have unexplained muscle pain,
tenderness, or weakness especially if you also have fever, unusual fatigue, and
dark colored urine problems.
Before
taking Losartan Potassium and Hydrochlorothiazide
You should take care of
all the above mentioned precautions mentioned above before taking Losartan
Potassium and Hydrochlorothiazide (Hyzaar, Losacar H). Discuss them with your
doctor and clear all the doubts about this medicine.
Dosage
Information
You should take Losartan
Potassium and Hydrochlorothiazide according to your doctor’s permission. Do not
alter the dosage unless your doctor advices you to do so. Do not take the
medicine if the prescription period is over. Always refer the instruction listed
on the medicine leaflet while taking the medicine. This medicine may take up to
4 weeks of regular intake to show the positive effect over high blood pressure.
It can be taken with or without food and you should swallow the tablet as a
whole with full glass of water. Always store the tablet in a cool and dry
place.
While taking Losartan Potassium and Hydrochlorothiazide, watch
out for the symptoms like vomiting, diarrhea or excessive sweating. All these
conditions can lead to severe dehydration which can further lower down your
blood pressure. It can be very dangerous as it may cause fatal conditions.
Consult your doctor if any of these conditions occur. You may have to take this
medicine for many years, even you may feel better.
What
if you miss a dose
If you miss a dose of
Losartan Potassium and Hydrochlorothiazide, try to take as soon as you remember
the dose. Always take care that you should not take the missed tablet if the
next dose time is close.
What
if you overdose
In case of overdose, seek
for an emergency medical treatment or call the Doctor. Overdose may cause
nausea, weakness, dizziness, dry mouth, thirst, muscle pain, weakness, or a
feeling like you might pass out.
Things
and activities to avoid
Avoid or limit the
consumption of alcoholic beverages. Do not become overheated or dehydrated
during the exercises and hot weather time. Always follow your doctor’s
instruction about what type of fluid you should prefer in your diet. It can
increase the potassium level in your body; hence avoid the intake of potassium
based supplements.
Side
Effects
Dizziness, light
headedness, swelling in ankles or feet, or flushing are some common side
effects that may be encountered during the usage. Also, some serious side
effects are there like fast, irregular or rapid heartbeat, or fainting, etc,
which may worsen the situation. Seek medical attention immediately and
contact your doctor right away.
Interaction
with other drugs
Many others drug may interact with Losartan Potassium and
Hydrochlorothiazide, inform your doctor well in advance if you are using
following products: (OTC vitamin pills or other medicines, or herbal products),
especially other blood pressure medicines, cholestyramine, cyclosporine,
rafmapin, ritonavir, barbiturates, muscle relaxers, narcotic medicines,
lithium, NSAIDs (ibuprofen, naproxen, or others), steroids, cholestyramine,
colestipol, insulin, oral diabetes medicines, a potassium supplement such as
K-Dur, Klor-Con, salt substitutes that contain potassium, or diuretics.
However, these are not only the drugs which interact with Losartan Potassium
and Hydrochlorothiazide. Never start a new medication without your doctor
permission.
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