Amlopres+ Valzar-5/160 MG

This drug is a combination of two active ingredients Amlodipine Besilate and Valsartan, which is mainly prescribed for the treatment of hypertension or high blood pressure. Amlodipine Besilate is a long acting dihydropyridine-type calcium channel blocker that prevents chest pain by relaxing heart and blood vessels. While, Valsartan is an Angiotensin II receptor antagonist that keeps blood vessels in a relaxed state. It is the common drug which is prescribed to reduce the hypertension and to prevent angina or chest pain.

How Amlodipine Besylate + Valsartan works?

Amlodipine Besylate works by inhibiting the movement of calcium ions via L type calcium channels into the vascular tissues and cardiac muscle cells. By restraining the entry of calcium channels, patients can decrease the contractility of arterial smooth muscles and causes vasodilation. It leads to relaxation of blood vessels which circulate the blood flow properly and reduces the overall blood pressure. The second important ingredient i.e.

Valsartan is a angiotensin II receptor blocker to angiotensin I, which is mainly found in tissues such as smooth muscles and adrenal glands. Angiotension exerts vasoconstriction and aldosterone effects and this inhibition results in dilation of blood vessels that reduces blood pressure. This combination drug helps patients to reduce the elevated level of blood pressure effectively.  

Important information about Amlodipine Besylate + Valsartan

You should not take Amlodipine Besylate+ Valsartan if you are strictly allergic to any of its constituents, or if you have liver problems, kidney diseases, diabetes, angina or coronary artery disease, heart disease or congestive heart failure. In case you are planning to become pregnant, you must consult your doctor while you are on the medicinal treatment with Amlodipine Besylate + Valsartan. Avoid this drug if you are breastfeeding. 

Dosage Information-

The drug should always be taken as prescribed by your doctor. You should follow the time table of drug to ensure maximum benefits. The general recommended dose starts from Amlodipine 10mg/ Valsartan 320 mg by the physician. It can be further increased to more strength depending upon the patient’s condition and demand. According to the progression of time and response of the patient, adjustments in the drugs can be done. Do not crush or chew the tablets, you must swallow the whole tablet with one glass full of water for best effects. Amlodipine Besylate is taken once daily with or without food. You should not stop taking this medicine suddenly unless your doctor advices you to do so. So, before stopping the drug usage, always consult your physician first. 

What if you miss a dose

If you miss a dose of Amlodipine Besylate+Valsartan, take the dose as soon as you remember. Be aware to skip the dose if the next dose time is almost up. Taking multiple dose can lead to excess medicine in your body which might cause critical conditions.   

What if you overdose

In case of overdose, get emergency medical help or call your doctor immediately. Overdose of this medicine may cause severe dizziness, vasodilation, hypotension, Bradycardia, Tachycardia, Circulatory collapse and shock. 

Things to avoid

Limit the intake of alcoholic beverages and avoid the activities which require high mental awareness because it may cause dizziness. Don’t use the medicine if the prescription period is over.  Don’t exceed the recommended dose.

Side Effects

All medicines have side effects, sometimes they affect lot but most of the time they are not. Some of the common side effects pertaining to this medicine are-cough, dizziness, headache, light headedness. While the serious side effects are- nausea, swelling in your hands and feet, irregular heartbeat, fever and chills, sore throat,  abdominal pain and discomfort, Rapid weight gain, Hyperkalemia conditions like bradycardia, weak pulse and muscle weakness, unexplained tiredness, skin bruising and yellowing of skin. Contact your doctor or seek medical attention immediately if you are experiencing these side effects.

Interaction with other drugs

 Many other drugs can interact with Amlodipine Besylate and Valsartan. The list of contraindicated drugs is as follows- Aliskiren, Conviptan, Drospirenone and other birth control pills, Lithium, Ibuprofen, Naproxen, Cough and cold products and Diet aids. Give a complete record of all the medicines you are taking along with Amlodipine Besylate and Valsartan. Never start a new medication without your doctor’s permission.  

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