Specification | |
US Brand Name | Lotrel |
Strength | 5 + 20 mg |
Generic Name | Amlodipine Besilate + Benazepril |
Manufacturer | No |
Pharmaceutical Form | NA |
Amlopres+
2 tabs of benace-5+20 MG
Amlopres
+ Benace- It can be expanded as Amlodipine Besylate plus Benazepril. The first
constituent Amlodipine Besylate is a long
acting dihydropyridine-type calcium channel blocker while the second
constituent Benazepril is an ACE inhibitor (Angiotensin
converting enzyme inhibitor). The fixed dose combination of both the
active ingredients is recommended for the treatment of hypertension and other
cardiovascular problems. This is the most popular drug which is
prescribed to reduce the hypertension and to prevent angina or chest pain.
Lowering the high blood pressure is helpful in reducing the heart strokes,
attacks and kidney problems. This drug is quite useful in building the exercise
capability by decreasing the frequency of angina attacks.
How
Amlodipine Besylate + Benazepril works?
Amlodipine Besylate works by inhibiting the movement of
calcium ions via L type calcium channels into the vascular tissues and cardiac
muscle cells. By restraining the entry of calcium channels, patients can
decrease the contractility of arterial smooth muscles and causes vasodilation.
It leads to relaxation of blood vessels which circulate the blood flow properly
and reduces the overall blood pressure. While, Benazepril is an ACE
(Angiotensin converting enzyme) inhibitor that also dilates blood vessels and
prevents body from retaining water. It reduces the post heart attack
damage by delivering sufficient amount of oxygen. In case of kidney problems,
it improves the blood supply in the kidney’s blood carrying vessels and lowers
down the chance of getting hypertension and post diabetes effects.
Important
information about Amlodipine
Besylate + Benazepril-
You should not take this drug if you are allergic to any of its
constituents, or if you have liver problems, unstable angina, porphyria,
congestive heart failure or any other heart problems. In case you are planning
to become pregnant, you must consult your doctor while you are on the medicinal
treatment with Amlopres + Benace.
Avoid this drug if you are breastfeeding.
Dosage
Information
The drug should always be
taken as prescribed by your doctor. You should follow the time table of drug to
ensure maximum benefits. Do not crush or chew the tablets, you must swallow the
whole tablet with one glass full of water for best effects. Amlodipine Besylate
is taken once daily with or without food. You should not stop taking this
medicine suddenly unless your doctor advices you to do so. So, before stopping
the drug usage, always consult your physician first.
What
if you miss a dose
If you miss a dose
of Amlodipine Besylate + Benazepril,
take the dose as soon as you remember. Be aware to skip the dose if the next
dose time is almost up. Taking multiple dose can lead to excess medicine in
your body which might cause critical conditions.
What
if you overdose
In case of overdose, get
emergency medical help or call your doctor immediately. Overdose of this
medicine may cause severe confusion, red skin rash, nausea, vomiting, diarrhea,
dizziness, rapid heart rate or fainting.
Things
to avoid
Limit the intake of
alcoholic beverages and avoid the activities which require high mental
awareness because it may cause dizziness. Don’t use the medicine if the
prescription period is over. Don’t exceed the recommended dose.
Side
Effects
All medicines have side
effects, sometimes they affect lot but most of the time they are not. Some of
the common side effects pertaining to this medicine are- nausea and vomiting,
dizziness, tired feeling, stomach pain, flushing, swelling of legs or ankles.
While the serious side effects are- lightheadedness, fast heartbeat, chest
pain, pain in arms or shoulders, general illness, fatigue. Contact your doctor
or seek medical attention immediately if you are experiencing these side
effects.
Interaction
with other drugs
Many other drugs can
interact with Amlodipine Besylate and Benazepril.
The list of contraindicated drugs is as follows- Dantrolene, Simvastatin,
Diltiazem, Ivacaftor, Nefazodone, Alfuzosin, Calcium carbonate, Calcium
chloride, Calcium citrate etc. Give a complete record of all the medicines you
are taking along with Amlodipine Besylate and Benazepril.
Never start a new medication without your doctor’s permission.
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