What is Adalat Chrono

This drug has a generic name Nifedipine, which is known as a calcium channel blocker drug, mainly prescribed for the treatment of hypertension (high blood pressure) and angina (chest pain). It dilates (widens) blood vessels and allows heart to pump blood easily through arteries and veins. This drug may also be used for other purposes which are not listed here. Nifedipine is sold under various trade names including Procardia, Myogard (manufactured by UPM), Nicardia (manufactured by Unique), Nifelat (manufactured by Cipla), and Adalat Chrono (manufactured by Bayer Healthcare).

Nifedipine blocks the slow calcium channel, preventing the flow of calcium ion into the cell. This drug produces peripheral and coronary vasodilatation, lower down afterload, peripheral resistance and BP. It increases coronary blood flow and causes reflex tachycardia. It effects little or negligible on cardiac conduction and rarely shows negative inotropic activities.

Important information about Nifedipine

You should not use Nifedipine (Procardia, Myogard, Nicardia, Nifelat, and Adalat Chrono), if you have allergic problems, severe coronary artery disease, or if you have had a heart attack in past two weeks. Before taking this medicine, let your doctor know if you have liver disease, a blockage in your digestive tract (stomach or intestines), a history of stomach surgery, coronary artery disease, or hypothyroidism. Before having a surgery or any other kind of operation, inform your health care personal that you are taking Nifedipine. 

It belongs to the class of FDA pregnancy category C drug. It is not accustomed whether the use of this drug is harmful for an unborn baby taken during the pregnancy or not. But, this medication can pass into the breast milk and can cause harms. You must consult your doctor before using the tablets in case of pregnancy and breast feeding.  

Dosage information

You should take the dosage of Nifedipine exactly as prescribed by your doctor. Follow all the direction listed on the leaflet of your medicine. Do not alter the dosage until it is being advised by the doctor. Also, do not use the medicine after prescription period is over. Store all the medicine in a cool and dry place, far away from the reach of children. Do not crush or chew the tablet, instead swallow it as a whole. Let your doctor know if you have excessive sweating, vomiting and diarrhea. These conditions can lead a severe low blood pressure.   

Note: Nifedipine dosage may depend on certain factors including age, sex, drug allergies, or seriousness of the condition among several other factors. Your dosage may determined by your physician after examining you properly. 

What if you miss a dose?

For effective results, you should take all medicines on the same time as prescribed. Missing even a single dose of Nifedipine can be harmful to your health. However, if you miss a dose of Nifidipine, then take it instantly, but avoid the use when next scheduled dose is near.

What if you overdose?

In case of an overdose of Nifedipine, seek emergency medication because it can cause severe dizziness, pounding heartbeats, nausea, vomiting, or feeling like you might pass out.

Things to avoid

Limit or avoid the consumption of alcohol. This drug might cause you dizzy. You should not drive and do any kind of activities that require high attentiveness until and unless you can do them safely. This drug might cause you dizzy. You should not drive and do any kind of activities that require high attentiveness until and unless you can do them safely. You should prohibit the use of grapefruit or the products made by it as they can interact with Nifedipine and results in dangerous effects.  

Side effects

Some common side effects caused by Nifedipine are dizziness, flushing, weakness, headache, swelling in ankles or feet. If any of these effects persist or deteriorate, kindly consult your doctor on the immediate basis. In rare cases, Nifedipine can worsen chest pain or cause heart attack in patients who already have heart diseases. This generally happens after starting this medication or increasing the amount of dose. Get medical attention right away if you experience certain severe conditions: worsening chest pain or the first sign of heart attack (pain in chest/jaw/left arm, shortness of breath, or unusual sweating.   

Interaction with other drugs

Many other drugs may interact with Nifedipine and causes serious side effects. Inform your doctor in advance if you are using any other drugs or related products (OTC vitamin pills or other medicines, or herbal products), especially cemitidine, conivaptan, digoxin, fentanyl, imatinib, isoniazid, laxatives, levothyroxine, nefazodone, NSAIDs (ibuprofen, naproxen, or others), cold or allergy medications, tizanidine, St.John’s Wort, HIV/AIDS medicines, antibiotics (clartithromycin, erythromycin, or others), or seizure medicines. Never start a new medication without your doctor permission.

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